The workshop Unravelling Cancer Cell Invasion and Metastasis will be held in the Molecular Biotechnology Center, Torino, on 2nd and 3rd December, 2010.

This workshop is the final conference of the Metafight Consortium and will bring together leading experts from European countries and USA.

MetaFight is a cooperative project funded by the European Commission through the 7th Framework Programme of Research and Development. This project regroups 10 institutions/companies working together with the goal to understand the dissemination and outgrowth of metastasis through systematic analysis of the Core Invasive Machinery contained within integrin-mediated ECM attachment structure.

Our strategy has been based on the hypothesis that metastatic cells arise from molecular changes that alter the primary tumour architecture as well as the tumor microenvironment, by reversible modulation of cell adhesion, onset of signalling pathways and acquisition of novel migratory and invasive capacities.

The MetaFight Consortium has been strengthened by established combined expertise on adhesion receptor signalling and availability of unique tumor cell and cancer animal model systems.

During the three year period, we have characterised known and novel components of the Core Invasive Machinery, responsible for development and homing of metastasis.

This workshop will indeed be an opportunity for researchers who are part of the MetaFight network and those who are not to summarize the present knowledge on cancer cell invasion and metastasis.